- A259 between A27 and Hampshire boundary, Hampshire (Grid ref SU740059)
- A259 between West Sussex boundary and Broad Road, West Sussex (Grid ref SU760057)
- A259 between Broad Road and A27 Chichester, West Sussex (Grid ref SU795053)
- A259 between A27 and A286, West Sussex (Grid ref SU854043)
- A259 between A286 and A27, West Sussex (Grid ref SU870046)
- A259 between A27(T) and Rowan Way, West Sussex (Grid ref SU899033)
- A259 between A27(T) and Brazwick Avenue, Bognor, West Sussex (Grid ref SU905030)
- A259 between A27(T) and Rowan Way, West Sussex (Grid ref SU905030)
- A259 between A27(T) and Rowan Way, West Sussex (Grid ref SU920009)
- A259 between A27(T) and Rowan Way, West Sussex (Grid ref SU931014)
- A259 between Brazwick Avenue and A29 roundabout, West Sussex (Grid ref SU933000)
- A259 between A29 and B2132, West Sussex (Grid ref SU948000)
- A259 between A259 and A29, West Sussex (Grid ref SU950019)
- A259 between B2132 Middleton Rd and Flansham Park, West Sussex (Grid ref SU962005)
- A259 between Flansham Park, Bognor and B2132 Yapton Rd (south), West Sussex (Grid ref SU970012)
- A259 between B2132 and B 2233, West Sussex (Grid ref SU980014)
- A259 between B2233 and New Courtwick Lane, Littlehampton, West Sussex (Grid ref TQ000018)
- A259 between New Courtwick Lane and A284, West Sussex (Grid ref TQ025034)
- A259 between A284 and B2187 Horsham Rd roundabout, West Sussex (Grid ref TQ030034)
- A259 between B2187 Horsham Rd roundabout and B2187 Mill Lane roundabout, West Sussex (Grid ref TQ050036)
- A259 between B2187 Mill Lane roundabout and A280, West Sussex (Grid ref TQ060031)
- A259 between A280 and B2140, West Sussex (Grid ref TQ070031)
- A259 between B2140 and A2032, West Sussex (Grid ref TQ100036)
- A259 between A2032 and A24, West Sussex (Grid ref TQ120026)
- A259 between A24 and A2025, West Sussex (Grid ref TQ155027)
- A259 between A2025 and A283 /VICTORIA Road, West Sussex (Grid ref TQ200042)
- A259 between A283 and West Sussex boundary, West Sussex (Grid ref TQ250050)
- A259 between Brighton and Hove boundary and B2193, Brighton and Hove (Grid ref TQ258049)
- A259 between B2193 and A2023, Brighton and Hove (Grid ref TQ280045)
- A259 between A2023 and A2010, Brighton and Hove (Grid ref TQ300041)
- A259 between A2010 and A23, Brighton and Hove (Grid ref TQ310039)
- A259 between A23 and B2137, Brighton and Hove (Grid ref TQ330034)
- A259 between B2137 Arundel Rd, Brighton and B2123 High Dt, Rottingdean, Brighton and Hove (Grid ref TQ355027)
- A259 between B2123 High St, Rottingdean and Brighton and Hove boundary, Brighton and Hove (Grid ref TQ375020)
- A259 between East Sussex boundary and South Way/Lewes Rd, East Sussex (Grid ref TQ400012)
- A259 between Brighton Rd and South Way, East Sussex (Grid ref TQ444015)
- A259 between Brighton Rd and North Way, East Sussex (Grid ref TQ445013)
- A259 between A259 North Way/ South Way and A259 spur to A26, East Sussex (Grid ref TQ449015)
- A259 between A259 main route and A26, East Sussex (Grid ref TQ450017)
- A259 between A26 and A259 The Drove roundabout, East Sussex (Grid ref TQ451016)
- A259 between A259 spur toA26 and A259 The Drove roundabout, East Sussex (Grid ref TQ451017)
- A259 between A259 Drove Road roundabout and B2109 Avis Rd, East Sussex (Grid ref TQ454019)
- A259 between B2109 Avis Rd and Bishopstone Rd, Seaford, East Sussex (Grid ref TQ460012)
- A259 between Bishopstone Rd and Alfriston Road, East Sussex (Grid ref TQ470001)
- A259 between Afriston Road and Chyngton Lane, East Sussex (Grid ref TV500992)
- A259 between Chyngton Lane, Seaford and Old Willingdon Road, East Dean, East Sussex (Grid ref TV530990)
- A259 between Old Willingdon Road, East Dean and Cherry Garden Rd, Eastbourne, East Sussex (Grid ref TV570980)
- A259 between Cherry Garden Rd and A22, East Sussex (Grid ref TV600994)
- A259 between A22 and A2040, East Sussex (Grid ref TV606993)
- A259 between A2040 and Ashford Road, East Sussex (Grid ref TV608991)
- A259 between Ashford Road/Terminus Road and Devonnshire Place, East Sussex (Grid ref TV610991)
- A259 between Ashford Road/Terminus Road and Devonshire Place, East Sussex (Grid ref TV613988)
- A259 between Susan's Road and A2021, East Sussex (Grid ref TV617990)
- A259 between A2021 and A2290, East Sussex (Grid ref TQ621001)
- A259 between B2104 and Pacific Drive, East Sussex (Grid ref TQ634020)
- A259 between Pacific Drive, Eastbourne and A27, East Sussex (Grid ref TQ650035)
- A259 between A27 and B2182 Cooden Sea Rd, East Sussex (Grid ref TQ660060)
- A259 between B2182 Cooden Sea Rd and A269, East Sussex (Grid ref TQ730080)
- A259 between A269W and A269E, East Sussex (Grid ref TQ739080)
- A259 between A269 and A2036, East Sussex (Grid ref TQ756080)
- A259 between A2036 and A259 principal, East Sussex (Grid ref TQ763080)
- A259 between A259 Trunk and A2102 London Road, East Sussex (Grid ref TQ800088)
- A259 between A2102 London Road and A2101 Harold Place, East Sussex (Grid ref TQ810091)
- A259 between A2101 Harold Place and A2101 Albert Road, East Sussex (Grid ref TQ818093)
- A259 between A2101 and B2093, East Sussex (Grid ref TQ828100)
- A259 between B2093 and A259 (trunk), East Sussex (Grid ref TQ840121)
- A259 between A259 principal and A268, East Sussex (Grid ref TQ919200)
- A259 between A268 Wish Street and A268 Fishmarket Road, East Sussex (Grid ref TQ920201)
- A259 between A268 and East Sussex boundary, East Sussex (Grid ref TQ939224)
- A259 between Kent boundary and B2080, Kent (Grid ref TR000264)
- A259 between B2080 and B2075, Kent (Grid ref TR050247)
- A259 between B2075 and B2071, Kent (Grid ref TR060246)
- A259 between B2071 and Palmarsh Road, Kent (Grid ref TR099290)
- A259 between Palmarsh Road and A2008, Kent (Grid ref TR142338)
- A259 between Palmarsh Avenue and A2008, Kent (Grid ref TR147341)
- A259 between A2008 and A261, Kent (Grid ref TR156346)
- A259 between A261 and Station Rd roundabout, Kent (Grid ref TR160346)
- A259 between Station Rd roundabout and B2063, Kent (Grid ref TR180349)
- A259 between B2063 and A2033, Kent (Grid ref TR200350)
- A259 between A2033 and A259 split, Kent (Grid ref TR220361)
- A259 between M20 Jct 13 and A260, Kent (Grid ref TR220378)
- A259 between Shorncliffe Rd and Cheriton Rd, Kent (Grid ref TR221362)
- A259 between A2034 and A2034, Kent (Grid ref TR221362)
- A259 between A2034 and Black Bull Rd, Kent (Grid ref TR222365)
- A259 between A2033 and A260, Kent (Grid ref TR228370)