- A721 between M73 / M74 and B7001 Old Edinburgh Rd, North Lanarkshire (Grid ref NS687619)
- A721 between B7001 Old Edinburgh Rd and A752, North Lanarkshire (Grid ref NS690616)
- A721 between A752 and A725, North Lanarkshire (Grid ref NS714605)
- A721 between A725 and B7070 North Road, North Lanarkshire (Grid ref NS730603)
- A721 between B7070 Hamilton Road and A721 Motherwell Rd, North Lanarkshire (Grid ref NS732602)
- A721 between B7070 Hamilton Road and B7070 North Road, North Lanarkshire (Grid ref NS732603)
- A721 between A721 Main St and A721 Hope St, North Lanarkshire (Grid ref NS734600)
- A721 between A721 Hope St and A723, North Lanarkshire (Grid ref NS751571)
- A721 between A723 and A721 Menteith Rd, North Lanarkshire (Grid ref NS752568)
- A721 between A723 and A721 Muir St, North Lanarkshire (Grid ref NS752573)
- A721 between A721 Brandon St and A723, North Lanarkshire (Grid ref NS753570)
- A721 between A721 Menteith Rd and A722, North Lanarkshire (Grid ref NS759561)
- A721 between A722 and A71, North Lanarkshire (Grid ref NS800547)
- A721 between A71 and A73, North Lanarkshire (Grid ref NS829539)
- A721 between A73 and B7056 Boghall Rd, South Lanarkshire (Grid ref NS855504)
- A721 between B7056 Boghall Rd and A706, South Lanarkshire (Grid ref NS881489)
- A721 between A706 and A70, South Lanarkshire (Grid ref NS920469)
- A721 between A70 and A702, South Lanarkshire (Grid ref NS997459)
- A721 between A702 and South Lanarkshire boundary, South Lanarkshire (Grid ref NT090442)
- A721 between Scottish Borders boundary and A72, Scottish Borders (Grid ref NT120444)