- A621 between A619 and B6051, Derbyshire (Grid ref SK281752)
- A621 between B6051 and B6054, Derbyshire (Grid ref SK294780)
- A621 between B6054 and Derbyshire boundary, Derbyshire (Grid ref SK296784)
- A621 between Sheffield boundary and Hillfoot Rd, Totley, Sheffield (Grid ref SK300793)
- A621 between Hillfoot Rd, Totley and B6068, Sheffield (Grid ref SK320808)
- A621 between B6068 and A61/A6100, Sheffield (Grid ref SK347850)
- A621 between A61 and A625, Sheffield (Grid ref SK351864)
- A621 between A61 and A61, Sheffield (Grid ref SK352860)
- A621 between A625 and Angel St, Sheffield (Grid ref SK356872)